How TNiC sources, grades, authors, reviews, and corrects its longevity content — stated plainly, including where independent clinical review is not yet in place.
Claims are tied to primary literature with direct PMID/DOI links wherever possible. The evidence model and how tiers are defined are described in the methodology. A citation is a pointer to a source — not, on its own, proof that a nearby claim is established. Where a source's population, intervention, comparator, duration, or endpoint does not match a claim, the claim should be downgraded or rewritten.
TNiC is moving from compound-level tier badges toward evidence graded at the level of a specific claim or outcome (mechanism vs. biomarker vs. clinical vs. lifespan), so a single "Tier A · Clinical" label can no longer sit on top of mechanistic or ex-vivo evidence. Until that migration is complete, some pages still show compound-level tiers; treat them as directional.
TNiC content is authored by the TNiC team. Author background is described on the About page.
Independent clinical review is not yet in place. Health content on this site is not currently reviewed by a named, credentialed clinician, pharmacist, or biostatistician. Until it is, pages should carry a "Not independently clinician-reviewed" status, and no content should be read as a personal recommendation. Establishing named independent reviewers is an owner action tracked in the project handoff.
Commercial links are disclosed and kept separate from evidence grading, per the sponsorship principles. Evidence tiers are never influenced by whether a compound is purchasable or sponsored.
Errors are fixed openly. See the corrections log and how to report one.
Editorial governance is being strengthened. This page states the current, honest status — including its gaps.