Evidence-Graded Longevity Library
See what
you're protecting.
You can't feel a cell aging. So we made it visible — the real biology behind your stack, rendered instead of promised. Five scenes. One continuous descent, from a molecule to the life it defends.
The molecule · rendered live
It starts smaller
than you can picture.
Trans-resveratrol — studied for sirtuin activation and healthy-aging pathways. Turn it over, zoom in. This is the actual shape doing the work, rendered live in your browser.
Rendered live · stylized for legibility, not a crystallographic reproduction
01 / System · Your stack, alive
Nothing works alone.
Every graded compound, plotted against the ones it boosts and the ones it clashes with. Turn the network over — the cool links are synergies, the amber ones are clashes, and the gold halos mark the TNiC elite picks. This is your stack as one connected system.
Rendered live · 8 elite picks haloed gold · synergies cool, clashes amber
02 / Goal · The honest dream
Not longer. Well, longer.
Longevity's real goal isn't just more years — it's keeping function high and pushing the decline into the very end. Drag through a life to watch the two paths separate. Toggle the elite protocol to see the ceiling a graded stack aims at.
Illustrative curves — the shape of the goal, not a number promised on any bottle. The gold area is the difference between fading early and staying well to the end. The cyan ceiling is what a graded stack aims at — no supplement is proven to land you there.
The path from here
You've seen the shape.
Now build to it.
Everything below this section is the working version of what you just watched — the elite interventions graded by human evidence, the full library of 100 compounds, and a NICO Starter Questionnaire that turns it into a stack pointed at your goals.
03 / Interventions
The compounds with the strongest human evidence — and where to buy them well.
8 nutrients that act on the hallmarks of aging, each graded by the strength of human trials (4 at Tier A), paired with one verified product that matches the dose and form used in the studies. Filter by hallmark, or open any card for the full evidence.
8 elite interventions
Glutathione Synthesis
GlyNAC
Rebuilds the glutathione antioxidant system
- Human studies cited
- 2
- Studied dose
- 600mg glycine + 600mg NAC
NAD+ Restoration
NMN
Restores NAD⁺ that powers sirtuins and DNA repair
- Human studies cited
- 3
- Studied dose
- 250–500mg NMN
TCA Cycle Support
Ca-AKG
Feeds the TCA cycle and α-ketoglutarate signalling
- Human studies cited
- 2
- Studied dose
- 1–2g Ca-AKG
NRF2 Activation
Sulforaphane
Switches on the NRF2 cellular-defense response
- Human studies cited
- 2
- Studied dose
- 10–35mg glucoraphanin
Sirtuin Activation
Trans-Resveratrol
Activates SIRT1, a caloric-restriction mimic
- Human studies cited
- 3
- Studied dose
- 150–500mg trans-resveratrol
Autophagy Induction
Spermidine
Induces autophagy — the cell’s self-cleanup pathway
- Human studies cited
- 2
- Studied dose
- 1–6mg spermidine (supplement) or dietary wheat germ
Osmolyte / Mitochondrial Buffer
Taurine
A mitochondrial osmolyte that declines with age
- Human studies cited
- 1
- Studied dose
- 1–3g taurine daily
Redox Cycling
R-Alpha Lipoic Acid
Recycles antioxidants across water and lipid compartments
- Human studies cited
- 1
- Studied dose
- 300–600mg R-ALA
How to read this.TNiC doesn't sell or stock supplements. Picks link to the manufacturer and may carry an affiliate token — at no extra cost to you, and commission never influences which products are listed or their evidence tier. This is educational information, not medical advice; talk to a clinician before starting anything, and always request a Certificate of Analysis before you buy.
04 / Mechanisms
Twelve mechanisms of aging. A ranked, cited intervention for each.
Every hallmark links to its highest-evidence levers — compounds, lifestyle changes, and clinical options — ranked by impact and traced to PubMed, not marketing copy.
05 / Protocol
From curious to confident — no account needed.
No sign-up, no upsell, no data leaving your device — just a clear path from the science to a decision you can stand behind.
STEP 01
Start with a hallmark or compound
Pick an aging mechanism you want to act on, or a nutrient you keep hearing about, and open its evidence page.
Open the librarySTEP 02
Read the graded evidence
See the human studies, the doses actually tested, and where each claim sits on the A–C scale — with every source linked.
See the 12 hallmarksSTEP 03
Decide what’s worth it
Use the buyer checklist to verify a product before you spend — and take your questions to a clinician before you start.
Open the buyer checklist
06 / Personalize
Your first move — computed for you.
Answer three quick questions and NICO assembles a personalized, evidence-graded starting stack pointed at your goals — with a built-in safety screen. Nothing is stored; everything runs on your device.
- Free forever
- Data stays on your device
- No account needed