All pathways
Signaling & Repair
eNOS / Nitric Oxide
The endothelial enzyme that makes nitric oxide — the signal that relaxes blood vessels.
Role in aging
Endothelial nitric-oxide synthase converts L-arginine to nitric oxide, driving vasodilation and healthy endothelial function. Age-related decline in NO availability underlies much vascular aging — the axis L-citrulline is studied to support.